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Top 100 prescribed drugs in Canada by Total Program Spending (TPS), sex, age group
|
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Jurisdiction
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Drug Class Code
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Drug Class
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Age Group
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Sex
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Tps In Thousands Of Dollars
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Proportion Of Tpspercent
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Rate Of Usepercent
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Number Of Active Beneficiaries
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Rank
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|---|---|---|---|---|---|---|---|---|---|---|
|
1
|
Canada
|
L04AB
|
Tumour necrosis factor alpha (TNF-a) inhibitors
|
Total
|
Total
|
1233882.07
|
8.2375
|
0.4673
|
65514
|
1
|
|
1
|
Canada
|
S01LA
|
Antineovascularization agents
|
Total
|
Total
|
774484.4
|
5.1705
|
0.571
|
80045
|
2
|
|
1
|
Canada
|
J05AP
|
Antivirals for treatment of HCV infections
|
Total
|
Total
|
638652.18
|
4.2637
|
0.0888
|
12444
|
3
|
|
1
|
Canada
|
L01XE
|
Protein kinase inhibitors
|
Total
|
Total
|
566185.41
|
3.7799
|
0.1093
|
15320
|
4
|
|
1
|
Canada
|
L04AA
|
Selective immunosuppressants
|
Total
|
Total
|
428442.41
|
2.8603
|
0.4156
|
58267
|
5
|
|
1
|
Canada
|
B01AF
|
Direct factor Xa inhibitors
|
Total
|
Total
|
402180.13
|
2.685
|
3.6545
|
512312
|
6
|
|
1
|
Canada
|
L04AX
|
Other immunosuppressants
|
Total
|
Total
|
400011.15
|
2.6705
|
0.2996
|
42006
|
7
|
|
1
|
Canada
|
N05AX
|
Other antipsychotics
|
Total
|
Total
|
332642.24
|
2.2208
|
2.1688
|
304034
|
8
|
|
1
|
Canada
|
R03AK
|
Adrenergics in combination with corticosteroids or other drugs, excluding anticholinergics
|
Total
|
Total
|
324088.21
|
2.1636
|
4.188
|
587098
|
9
|
|
1
|
Canada
|
C10AA
|
HMG-CoA reductase inhibitors
|
Total
|
Total
|
306978.74
|
2.0494
|
26.428
|
3704811
|
10
|
|
1
|
Canada
|
A02BC
|
Proton pump inhibitors
|
Total
|
Total
|
254727.9
|
1.7006
|
19.6007
|
2747723
|
11
|
|
1
|
Canada
|
A10BH
|
Dipeptidyl peptidase-4 (DPP-4) inhibitors
|
Total
|
Total
|
246029.51
|
1.6425
|
2.134
|
299151
|
12
|
|
1
|
Canada
|
A10AE
|
Insulins and analogues for injection, long-acting
|
Total
|
Total
|
245020.81
|
1.6358
|
2.2806
|
319705
|
13
|
|
1
|
Canada
|
A10BD
|
Combinations of oral blood glucose–lowering drugs
|
Total
|
Total
|
244783.22
|
1.6342
|
2.0202
|
283201
|
14
|
|
1
|
Canada
|
A10BK
|
Sodium–glucose co-transporter 2 (SGLT2) inhibitors
|
Total
|
Total
|
215171.79
|
1.4365
|
2.1412
|
300171
|
15
|
|
1
|
Canada
|
J05AR
|
Antivirals for treatment of HIV infections, combinations
|
Total
|
Total
|
212218.46
|
1.4168
|
0.1957
|
27439
|
16
|
|
1
|
Canada
|
N06AX
|
Other antidepressants
|
Total
|
Total
|
208039.1
|
1.3889
|
9.7029
|
1360197
|
17
|
|
1
|
Canada
|
L04AC
|
Interleukin inhibitors
|
Total
|
Total
|
201112.98
|
1.3427
|
0.0985
|
13809
|
18
|
|
1
|
Canada
|
N03AX
|
Other antiepileptics
|
Total
|
Total
|
197957.05
|
1.3216
|
6.9027
|
967662
|
19
|
|
1
|
Canada
|
N07BC
|
Drugs used in opioid dependence
|
Total
|
Total
|
197212.16
|
1.3166
|
0.7775
|
108992
|
20
|
|
1
|
Canada
|
N05AH
|
Diazepines, oxazepines, thiazepines and oxepines
|
Total
|
Total
|
181800.01
|
1.2137
|
4.0301
|
564956
|
21
|
|
1
|
Canada
|
N06AB
|
Selective serotonin reuptake inhibitors
|
Total
|
Total
|
176247.29
|
1.1766
|
10.9732
|
1538280
|
22
|
|
1
|
Canada
|
C08CA
|
Dihydropyridine derivatives
|
Total
|
Total
|
166633.12
|
1.1125
|
12.1599
|
1704642
|
23
|
|
1
|
Canada
|
N02AA
|
Natural opium alkaloids
|
Total
|
Total
|
165891.67
|
1.1075
|
5.6114
|
786641
|
24
|
|
1
|
Canada
|
R03BB
|
Anticholinergics
|
Total
|
Total
|
152173.31
|
1.0159
|
3.4343
|
481445
|
25
|
|
1
|
Canada
|
N06BA
|
Centrally acting sympathomimetics
|
Total
|
Total
|
151371.61
|
1.0106
|
2.3455
|
328809
|
26
|
|
1
|
Canada
|
C09AA
|
ACE inhibitors, plain
|
Total
|
Total
|
145400.45
|
0.9707
|
13.1721
|
1846540
|
27
|
|
1
|
Canada
|
M05BX
|
Other drugs affecting bone structure and mineralization
|
Total
|
Total
|
132464.13
|
0.8843
|
1.3517
|
189492
|
28
|
|
1
|
Canada
|
C09CA
|
Angiotensin II receptor blockers (ARBs), plain
|
Total
|
Total
|
126656.99
|
0.8456
|
8.6343
|
1210401
|
29
|
|
1
|
Canada
|
C07AB
|
Beta-blocking agents, selective
|
Total
|
Total
|
115358.25
|
0.7701
|
11.4098
|
1599483
|
30
|
|
1
|
Canada
|
R03BA
|
Glucocorticoids
|
Total
|
Total
|
113614.71
|
0.7585
|
6.0082
|
842257
|
31
|
|
1
|
Canada
|
L02AE
|
Gonadotropin-releasing hormone analogues
|
Total
|
Total
|
104197.55
|
0.6956
|
0.2467
|
34586
|
32
|
|
1
|
Canada
|
A10AB
|
Insulins and analogues for injection, fast-acting
|
Total
|
Total
|
103375.93
|
0.6901
|
1.6902
|
236935
|
33
|
|
1
|
Canada
|
H03AA
|
Thyroid hormones
|
Total
|
Total
|
99842.7
|
0.6666
|
11.1214
|
1559049
|
34
|
|
1
|
Canada
|
L03AA
|
Colony-stimulating factors
|
Total
|
Total
|
87752.16
|
0.5858
|
0.1284
|
18003
|
35
|
|
1
|
Canada
|
B03XA
|
Other antianemic preparations
|
Total
|
Total
|
87254.14
|
0.5825
|
0.1282
|
17974
|
36
|
|
1
|
Canada
|
B01AC
|
Platelet aggregation inhibitors, excluding heparin
|
Total
|
Total
|
85119.84
|
0.5683
|
2.8768
|
403291
|
37
|
|
1
|
Canada
|
R03DX
|
Other systemic drugs for obstructive airway diseases
|
Total
|
Total
|
83428.88
|
0.557
|
0.0402
|
5638
|
38
|
|
1
|
Canada
|
M05BA
|
Bisphosphonates
|
Total
|
Total
|
81561.23
|
0.5445
|
3.2744
|
459022
|
39
|
|
1
|
Canada
|
G04BD
|
Drugs for urinary frequency and incontinence
|
Total
|
Total
|
79169.57
|
0.5285
|
1.9831
|
278005
|
40
|
|
1
|
Canada
|
B01AB
|
Heparin group
|
Total
|
Total
|
74299.5
|
0.496
|
0.5004
|
70152
|
41
|
|
1
|
Canada
|
L02BX
|
Other hormone antagonists and related agents
|
Total
|
Total
|
74004.74
|
0.4941
|
0.0337
|
4718
|
42
|
|
1
|
Canada
|
A10BA
|
Biguanides
|
Total
|
Total
|
72198.32
|
0.482
|
8.6755
|
1216175
|
43
|
|
1
|
Canada
|
H01CB
|
Somatostatin and analogues
|
Total
|
Total
|
71497.4
|
0.4773
|
0.0335
|
4700
|
44
|
|
1
|
Canada
|
G04CA
|
Alpha-adrenoreceptor antagonists
|
Total
|
Total
|
70327.27
|
0.4695
|
4.9248
|
690391
|
45
|
|
1
|
Canada
|
R03AC
|
Selective beta-2-adrenoreceptor agonists
|
Total
|
Total
|
65485.14
|
0.4372
|
12.775
|
1790869
|
46
|
|
1
|
Canada
|
L04AD
|
Calcineurin inhibitors
|
Total
|
Total
|
63134.44
|
0.4215
|
0.1452
|
20356
|
47
|
|
1
|
Canada
|
M03AX
|
Other muscle relaxants, peripherally acting agents
|
Total
|
Total
|
62743.59
|
0.4189
|
0.2145
|
30065
|
48
|
|
1
|
Canada
|
N05BA
|
Benzodiazepine derivatives
|
Total
|
Total
|
62642.55
|
0.4182
|
7.7109
|
1080957
|
49
|
|
1
|
Canada
|
S01EE
|
Prostaglandin analogues
|
Total
|
Total
|
61820.65
|
0.4127
|
2.1817
|
305843
|
50
|
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