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Top 100 prescribed drugs in Canada by Total Program Spending (TPS), sex, age group

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Drug Class Code

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Drug Class

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Age Group

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Sex

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Tps In Thousands Of Dollars

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Proportion Of Tpspercent

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Rate Of Usepercent

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Number Of Active Beneficiaries

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Rank

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1
Canada
L04AB
Tumour necrosis factor alpha (TNF-a) inhibitors
Total
Total
1233882.07
8.2375
0.4673
65514
1
1
Canada
S01LA
Antineovascularization agents
Total
Total
774484.4
5.1705
0.571
80045
2
1
Canada
J05AP
Antivirals for treatment of HCV infections
Total
Total
638652.18
4.2637
0.0888
12444
3
1
Canada
L01XE
Protein kinase inhibitors
Total
Total
566185.41
3.7799
0.1093
15320
4
1
Canada
L04AA
Selective immunosuppressants
Total
Total
428442.41
2.8603
0.4156
58267
5
1
Canada
B01AF
Direct factor Xa inhibitors
Total
Total
402180.13
2.685
3.6545
512312
6
1
Canada
L04AX
Other immunosuppressants
Total
Total
400011.15
2.6705
0.2996
42006
7
1
Canada
N05AX
Other antipsychotics
Total
Total
332642.24
2.2208
2.1688
304034
8
1
Canada
R03AK
Adrenergics in combination with corticosteroids or other drugs, excluding anticholinergics
Total
Total
324088.21
2.1636
4.188
587098
9
1
Canada
C10AA
HMG-CoA reductase inhibitors
Total
Total
306978.74
2.0494
26.428
3704811
10
1
Canada
A02BC
Proton pump inhibitors
Total
Total
254727.9
1.7006
19.6007
2747723
11
1
Canada
A10BH
Dipeptidyl peptidase-4 (DPP-4) inhibitors
Total
Total
246029.51
1.6425
2.134
299151
12
1
Canada
A10AE
Insulins and analogues for injection, long-acting
Total
Total
245020.81
1.6358
2.2806
319705
13
1
Canada
A10BD
Combinations of oral blood glucose–lowering drugs
Total
Total
244783.22
1.6342
2.0202
283201
14
1
Canada
A10BK
Sodium–glucose co-transporter 2 (SGLT2) inhibitors
Total
Total
215171.79
1.4365
2.1412
300171
15
1
Canada
J05AR
Antivirals for treatment of HIV infections, combinations
Total
Total
212218.46
1.4168
0.1957
27439
16
1
Canada
N06AX
Other antidepressants
Total
Total
208039.1
1.3889
9.7029
1360197
17
1
Canada
L04AC
Interleukin inhibitors
Total
Total
201112.98
1.3427
0.0985
13809
18
1
Canada
N03AX
Other antiepileptics
Total
Total
197957.05
1.3216
6.9027
967662
19
1
Canada
N07BC
Drugs used in opioid dependence
Total
Total
197212.16
1.3166
0.7775
108992
20
1
Canada
N05AH
Diazepines, oxazepines, thiazepines and oxepines
Total
Total
181800.01
1.2137
4.0301
564956
21
1
Canada
N06AB
Selective serotonin reuptake inhibitors
Total
Total
176247.29
1.1766
10.9732
1538280
22
1
Canada
C08CA
Dihydropyridine derivatives
Total
Total
166633.12
1.1125
12.1599
1704642
23
1
Canada
N02AA
Natural opium alkaloids
Total
Total
165891.67
1.1075
5.6114
786641
24
1
Canada
R03BB
Anticholinergics
Total
Total
152173.31
1.0159
3.4343
481445
25
1
Canada
N06BA
Centrally acting sympathomimetics
Total
Total
151371.61
1.0106
2.3455
328809
26
1
Canada
C09AA
ACE inhibitors, plain
Total
Total
145400.45
0.9707
13.1721
1846540
27
1
Canada
M05BX
Other drugs affecting bone structure and mineralization
Total
Total
132464.13
0.8843
1.3517
189492
28
1
Canada
C09CA
Angiotensin II receptor blockers (ARBs), plain
Total
Total
126656.99
0.8456
8.6343
1210401
29
1
Canada
C07AB
Beta-blocking agents, selective
Total
Total
115358.25
0.7701
11.4098
1599483
30
1
Canada
R03BA
Glucocorticoids
Total
Total
113614.71
0.7585
6.0082
842257
31
1
Canada
L02AE
Gonadotropin-releasing hormone analogues
Total
Total
104197.55
0.6956
0.2467
34586
32
1
Canada
A10AB
Insulins and analogues for injection, fast-acting
Total
Total
103375.93
0.6901
1.6902
236935
33
1
Canada
H03AA
Thyroid hormones
Total
Total
99842.7
0.6666
11.1214
1559049
34
1
Canada
L03AA
Colony-stimulating factors
Total
Total
87752.16
0.5858
0.1284
18003
35
1
Canada
B03XA
Other antianemic preparations
Total
Total
87254.14
0.5825
0.1282
17974
36
1
Canada
B01AC
Platelet aggregation inhibitors, excluding heparin
Total
Total
85119.84
0.5683
2.8768
403291
37
1
Canada
R03DX
Other systemic drugs for obstructive airway diseases
Total
Total
83428.88
0.557
0.0402
5638
38
1
Canada
M05BA
Bisphosphonates
Total
Total
81561.23
0.5445
3.2744
459022
39
1
Canada
G04BD
Drugs for urinary frequency and incontinence
Total
Total
79169.57
0.5285
1.9831
278005
40
1
Canada
B01AB
Heparin group
Total
Total
74299.5
0.496
0.5004
70152
41
1
Canada
L02BX
Other hormone antagonists and related agents
Total
Total
74004.74
0.4941
0.0337
4718
42
1
Canada
A10BA
Biguanides
Total
Total
72198.32
0.482
8.6755
1216175
43
1
Canada
H01CB
Somatostatin and analogues
Total
Total
71497.4
0.4773
0.0335
4700
44
1
Canada
G04CA
Alpha-adrenoreceptor antagonists
Total
Total
70327.27
0.4695
4.9248
690391
45
1
Canada
R03AC
Selective beta-2-adrenoreceptor agonists
Total
Total
65485.14
0.4372
12.775
1790869
46
1
Canada
L04AD
Calcineurin inhibitors
Total
Total
63134.44
0.4215
0.1452
20356
47
1
Canada
M03AX
Other muscle relaxants, peripherally acting agents
Total
Total
62743.59
0.4189
0.2145
30065
48
1
Canada
N05BA
Benzodiazepine derivatives
Total
Total
62642.55
0.4182
7.7109
1080957
49
1
Canada
S01EE
Prostaglandin analogues
Total
Total
61820.65
0.4127
2.1817
305843
50

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